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Testosterone replacement therapy (trt) is form of medical treatment primarily used to treat symptoms of sexual dysfunction in men and women. Summarize current class indication for testosterone replacement therapy (trt) products. • outline the current trt drug development paradigm. This treatment is called testosterone replacement therapy, or trt. Clinical hypogonadism is the only fda-approved indication for trt in men; it is not approved to treat age-related low testosterone. Testosterone replacement therapy is the medical treatment of a patient that provides. In this study, we evaluated the risk of myocardial infarction (mi) associated with trt in hypogonadal men through a meta-analysis. Testosterone replacement therapy, also called androgen replacement therapy, is approved to treat male hypogonadism (low testosterone or “low t”),. 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